Vol. 9, 2024
Radiobiology
POST–ACCIDENT BIOTA OF SERIOUS AND MAJOR RADIATION ACCIDENTS AND RADIOADAPTATION
N.M. Lyubashevsky, V.I. Starichenko
Pages: 114-120
DOI: 10.37392/RapProc.2024.22
Abstract | References | Full Text (PDF)
The hypothesis of potentially lethal effects on biota during serious and major radiation accidents (SMA) is presented as a key event determining the characteristics of post-accident biota. At the same time, its actual observed state is the result of an evolutionarily fixed adequate reactivity to the risk of extinction. The programmed radioprotective–adaptive response includes epigenetic modifications and all levels of bioorganization, from molecular, intrapopulation (maternal effect, biosocial processes, etc.), to the formation of radiation ecosystems. The universality and effectiveness of this reactivity are the main indicator of overcoming biota extinction. Multiple anomalies imitating the effects of reduced radioresistance are also markers of damage. However, increased sensitivity to radiation in the natural environment is incompatible with the basic principles of biodiversity, which increases resistance to stress. Therefore, suppression of radioresistance cannot serve as an alternative to potentially lethal irradiation by SMA. Real SMA radiation loads are an order of magnitude lower than the doses characteristic of the observed damage to biota, ranked in laboratory and controlled conditions. It has been shown that the abnormally high radiotoxic load in SMA is provided by the synergy of damaging factors, both physical (acute/subacute + chronic irradiation) and biological (two– and multicomponent), to one degree or another associated with mutagenesis. In the early stages, for example, in rodents – hematological syndrome, then mainly reproductive damage, genetic drift, synergistically enhanced by a small population size. A constant level of increased mutagenesis against the background of a decrease in the absorbed dose may indicate a molecular-adaptive mechanism for blocking the synthesis products of damaged DNA (proteins, mRNA). Radioadaptation depends on isolation: animals living in families in an underground colony (mole vole Ellobius talpinus Pallas, 1770) are perfectly adapted, i.e. without anomalies, while the adaptation of mobile terrestrial rodents is imperfect. Radioadaptation is widely represented in the post–accident biota of the Chernobyl disaster under conditions of epigenetic transgenerational heredity. However, its implementation in the experiment has not been noted.
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